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Updated: Mar 16, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
Published on: June 28, 2019
Improved myocardial perfusion after transmyocardial laser revascularization in a patient with microvascular coronary
Peyman Mesbah Oskui1, Guy S Mayeda2, Steven Burstein2
1Department of Cardiology, Harbor-UCLA Medical Center, Torrance, CA, USA; Heart Institute, Good Samaritan Hospital, Los Angeles, CA, USA.
Abstract:
We report the case of a 59-year-old woman who presented with symptoms of angina that was refractory to medical management. Although her cardiac catheterization revealed microvascular coronary artery disease, her symptoms were refractory to optimal medical management that included ranolazine. After undergoing transmyocardial revascularization, her myocardial ischemia completely resolved and her symptoms dramatically improved. This case suggests that combination of ranolazine and transmyocardial revascularization can be applied to patients with microvascular coronary artery disease.
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