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Updated: Jan 29, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Recurrent hydropneumothorax: An unusual presentation for malignant pleural mesothelioma
David DeLapp1, Christopher Chan1, Perry Nystrom2
1Wright State University Boonshoft School of Medicine Internal Medicine Program, Miami Valley Hospital, Weber CHE Building, 128 E. Apple St., 2nd Floor, Dayton, OH, 45409, USA.
Abstract:
Mesothelioma is a rare pulmonary malignancy commonly associated with asbestos exposure. Its presentation is insidious and non-specific, with complaints of chest pain, dyspnea and cough. Chest X-ray may demonstrate unilateral pleural effusion. CT and PET scans may highlight nodular pleural plaques. Diagnosis often times is difficult with negative imaging and negative pleural fluid studies. In rare cases, hydropneumothoraces may be seen. We report a case of malignant pleural mesothelioma presenting as recurrent hydropneumothorax with negative CT scan of the chest for pleural abnormalities and negative pleural fluid studies.
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