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Effects of glutathione isopropyl ester on glutathione concentration in ischemic rat brain
K Noguchi1, S Higuchi, H Matsui
1Drug Metabolism Department, Yamanouchi Pharmaceutical Co., Ltd., Tokyo, Japan.
Research Communications in Chemical Pathology and Pharmacology
|April 1, 1989
Abstract:
Glutathione concentrations in ischemic rat brain induced by ligation of bilateral carotid arteries were decreased significantly. Intraperitoneal administration of glutathione isopropyl ester maintained glutathione concentrations in ischemic rat brain at the normal level, while glutathione manifested no effects.