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Converting relative risks to absolute risks: a graphical approach.

W D Dupont1

  • 1Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-2637.

Statistics in Medicine
|June 1, 1989
PubMed
Summary
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This study introduces a graphical method to convert relative cancer risks into absolute risks, considering age and other causes of death. These tools aid clinical decision-making and patient counseling for better risk communication.

Area of Science:

  • Epidemiology
  • Biostatistics
  • Medical Informatics

Background:

  • Translating relative risk into absolute risk is crucial for clinical decision-making.
  • Existing methods may not adequately account for competing mortality risks.
  • Graphical representations can enhance understanding of complex risk data.

Purpose of the Study:

  • To present a novel graphical method for converting relative risks to absolute risks.
  • To illustrate the impact of competing mortality on absolute cancer risk.
  • To provide tools for clinical decision-making and patient counseling.

Main Methods:

  • Developed a graphical approach to estimate absolute risk based on age, relative risk, baseline hazard, and competing risks.
  • Applied the proportional hazards model for risk estimation.

Related Experiment Videos

  • Included an exponential hazards model for comparison.

    • Main Results:

    • Generated graphs for breast cancer morbidity, cardiovascular mortality, and lung cancer morbidity.
    • Demonstrated the influence of competing mortality on absolute cancer risk predictions.
    • Showcased the utility of graphs in visualizing 20-year cancer probability.

    Conclusions:

    • The graphical method effectively converts relative risks to absolute risks.
    • Competing mortality significantly impacts absolute cancer risk.
    • The presented graphs serve as valuable aids for clinical practice and patient communication.