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Published on: November 15, 2024
[Alcohol consumption in women and the elderly : When does it induce heart failure?]
1Klinik für Innere Medizin - Kardiologie, Philipps-Universität Marburg, Baldingerstraße, 35043, Marburg, Deutschland. pankuwei@staff.uni-marburg.de.
Insights
Alcohol
Area of Science:
- Cardiology
- Public Health
- Toxicology
Background:
- The relationship between alcohol consumption and cardiovascular diseases (CVDs) is complex and debated.
- Heart failure etiology includes coronary artery disease (CAD), hypertension, arrhythmias, and cardiomyopathies.
- Alcohol's acute and chronic effects on the heart range from rhythm disturbances to cardiomyopathy.
Purpose of the Study:
- To review the multifaceted effects of alcohol consumption on cardiovascular disease etiology and prognosis.
- To differentiate impacts of acute vs. chronic, and light/moderate vs. heavy alcohol intake.
- To examine sex-based and age-related differences in alcohol's cardiovascular effects.
Main Methods:
- Literature review and synthesis of existing research on alcohol and cardiovascular health.
- Analysis of studies examining acute and chronic alcohol exposure.
- Comparison of cardiovascular risks across different consumption levels and demographics.
Main Results:
- High alcohol doses cause acute cardiac issues (e.g., holiday heart syndrome) and chronic problems (e.g., alcoholic cardiomyopathy, CAD).
- Light to moderate alcohol intake correlates with reduced risk of coronary artery disease (CAD) and ischemic stroke.
- Moderate drinking increases atrial fibrillation risk; women are more susceptible to adverse effects at lower consumption levels.
Conclusions:
- Alcohol's cardiovascular impact is dose-dependent and varies with consumption patterns.
- While moderate intake may offer some protection against CAD and stroke, it elevates atrial fibrillation risk.
- Understanding these nuances is crucial for personalized cardiovascular risk assessment and public health guidance.
Abstract:
The association between alcohol consumption and the etiology and prognosis of cardiovascular diseases has been the focus of attention and also the subject of controversial discussions for many years. This is particularly true for heart failure, which can be induced by coronary artery disease (CAD), arterial hypertension, atrial and ventricular arrhythmias and cardiomyopathies. Acute effects of high doses of alcohol can lead to impairment of the cardiac contraction strength with rhythm disturbances (holiday heart syndrome), transient ischemic attacks and in rare cases to sudden cardiac death. The chronic effects of high alcohol consumption include in particular, ventricular dysfunction, chronic rhythm disturbances, alcoholic cardiomyopathy and CAD. In contrast, light to moderate consumption of alcohol is associated with a reduced risk of CAD and ischemic stroke; however, even moderate alcohol drinking is associated with a greater risk for atrial fibrillation. The unfavorable effects of alcohol occur at much lower levels of acute or chronic consumption in women than in men. In the elderly just as in young people, a moderate alcohol consumption is associated with a lower risk of heart failure.
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