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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
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Perinatal management: What has been learned through the network?

Sanjay Chawla1, Elizabeth E Foglia2, Vishal Kapadia3

  • 1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Wayne State University, Detroit, MI.

Seminars in Perinatology
|August 6, 2016
PubMed
Summary

The Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network (NRN) studied interventions for preterm infants. Their research informs neonatal resuscitation guidelines and family counseling on resuscitation appropriateness.

Keywords:
antenatal steroidsdelivery roomneonatal resuscitationperinatal

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Area of Science:

  • Neonatology
  • Perinatal Medicine
  • Pediatric Research

Background:

  • The Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network (NRN) focuses on neonatal outcomes, especially for preterm infants.
  • Obstetrical and neonatal delivery room practices significantly impact newborn health.

Purpose of the Study:

  • To examine the effects of various obstetrical, perinatal, and neonatal delivery room interventions on newborns, with a focus on preterm infants.
  • To review NRN studies informing neonatal resuscitation guidelines and provider counseling.

Main Methods:

  • Review of NRN studies on maternal medications, delivery route/timing, cord clamping, euthermia, ventilation, and cardiopulmonary resuscitation.
  • Analysis of outcome data for infants at the lowest gestational ages.

Main Results:

  • NRN research has contributed key evidence to international neonatal resuscitation guidelines.
  • Studies addressed timing of cord clamping, maintaining euthermia, ventilation strategies, and cardiopulmonary resuscitation outcomes.
  • Outcome data at extremely low gestational ages influences counseling on resuscitation appropriateness.

Conclusions:

  • NRN research provides critical evidence for neonatal care practices and resuscitation guidelines.
  • The network's findings impact clinical decision-making and family counseling for high-risk newborns.
  • Continued research by the NRN is vital for improving outcomes in preterm infants.