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Kasabach - Merritt syndrome: A case report
1Paediatric and Child health Department , Omdurman Islamic University. Omdurman , Sudan.
Abstract:
Kasabach-Merritt syndrome is characterised by the combination of rapidly growing vascular tumour, thrombocytopenia, microangiopathic haemolytic anaemia and consumptive coagulopathy. The blood clotting disorder results from platelets and other clotting factors of the blood being used up within the tumor. We report a two- and- half month old Saudi female infant who presented with epistaxis, conjunctival haemorrage and bilateral periorbital ecchymosis.
Insights
Kasabach-Merritt syndrome involves vascular tumors and blood clotting issues. This case highlights a rare presentation in a Saudi infant with bleeding symptoms.
Area of Science:
- Pediatric Hematology
- Vascular Anomalies
- Coagulation Disorders
Background:
- Kasabach-Merritt syndrome (KMS) is a rare condition.
- It is characterized by a vascular tumor, thrombocytopenia, microangiopathic hemolytic anemia, and consumptive coagulopathy.
- The syndrome arises from platelets and clotting factors being consumed within the tumor.
Observation:
- A two-and-a-half-month-old Saudi female infant presented with significant bleeding.
- Symptoms included epistaxis (nosebleeds), conjunctival hemorrhage, and bilateral periorbital ecchymosis (bruising around the eyes).
Findings:
- The infant's presentation suggests a potential diagnosis of Kasabach-Merritt syndrome.
- This highlights the diverse clinical manifestations of KMS in infants.
- Early recognition of bleeding symptoms is crucial for timely diagnosis.
Implications:
- This case underscores the importance of considering KMS in infants with unexplained bleeding and vascular tumors.
- Prompt diagnosis and management are vital to prevent severe complications.
- Further research into the pathogenesis and treatment of KMS is warranted.
