Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mutations01:35

Mutations

45.3K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
45.3K
Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview01:02

Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview

8.4K
Ultraviolet–visible (UV–visible or UV–Vis) spectroscopy is an analytical technique that investigates the interaction between matter and UV–Vis light within the electromagnetic spectrum. This method is widely used for its versatility, simplicity, and relatively quick data acquisition, making it valuable for both qualitative and quantitative analysis. When UV–Vis radiation passes through a material,  molecules absorb light depending on the energy required for...
8.4K
UV–Vis Spectrometers01:14

UV–Vis Spectrometers

4.3K
The absorbance of UV and visible (UV–visible) radiations is measured using a UV–visible spectrophotometer. Deuterium lamps, which emit UV radiation, and tungsten lamps, which produce radiation in the visible region, are used as light sources in UV–visible spectrophotometers. A monochromator or prism is used for diffraction grating, i.e., to split the incoming radiation into different wavelengths. A system of slits is used to focus the desired wavelength on the sample cell.
4.3K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

41.6K
Overview
41.6K
Nucleotide Excision Repair01:38

Nucleotide Excision Repair

5.6K
DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.6K
UV–Vis Spectroscopy: Molecular Electronic Transitions01:16

UV–Vis Spectroscopy: Molecular Electronic Transitions

3.4K
In Ultraviolet–Visible (UV–Vis) spectroscopy, the absorption of electromagnetic radiation is used to probe the electronic structure of molecules. This technique provides insights into molecular electronic transitions, particularly the movement of electrons between different molecular orbitals. Radiation is absorbed if the energy of the electromagnetic radiation passing through the molecule is precisely equal to the energy difference between the excited and ground states. During this...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Consequences of changing illumination procedures in photodynamic therapy.

Photodiagnosis and photodynamic therapy·2026
Same author

SRBench++ : principled benchmarking of symbolic regression with domain-expert interpretation.

IEEE transactions on evolutionary computation : a publication of the IEEE Neural Networks Council·2025
Same author

Invited review: The One Health challenges and opportunities of the H5N1 outbreak in dairy cattle in the United States.

Journal of dairy science·2025
Same author

Ultraviolet radiation protection factors of livestock shade cloths for free-range pigs.

Veterinary dermatology·2024
Same author

Cyclic photodynamic therapy delays first onset of actinic keratoses in renal transplant recipients: a 5-year randomized controlled trial with 12-month follow-up.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Ultraviolet radiation exposure to the face in patients with xeroderma pigmentosum and healthy controls: applying a novel methodology to define photoprotection behaviour.

The British journal of dermatology·2021

Related Experiment Video

Updated: Mar 16, 2026

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

2.2K

Defining "intermittent UVR exposure".

M Bodekær1, P A Philipsen1, B Petersen1

  • 1Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark. mettebodek@hotmail.com.

Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology
|August 6, 2016
PubMed
Summary

Researchers defined intermittent ultraviolet radiation (UVR) exposure using objective dosimetry. This new measure better predicts skin damage and cutaneous malignant melanoma (CMM) risk than questionnaires.

More Related Videos

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K
Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
13:56

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

10.4K

Related Experiment Videos

Last Updated: Mar 16, 2026

Studying Chronic Exposure of Mice to Ultraviolet B Radiation
03:20

Studying Chronic Exposure of Mice to Ultraviolet B Radiation

Published on: August 19, 2025

2.2K
Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

13.3K
Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract
13:56

Characterization of Molecular Mechanisms of In vivo UVR Induced Cataract

Published on: November 28, 2012

10.4K

Area of Science:

  • Dermatology
  • Environmental Health
  • Epidemiology

Background:

  • Cutaneous malignant melanoma (CMM) is linked to intermittent ultraviolet radiation (UVR) exposure.
  • Previous assessments relied on retrospective questionnaires, lacking a uniform definition for intermittent UVR exposure.

Purpose of the Study:

  • To objectively define and quantify intermittent UVR exposure.
  • To compare the predictive power of an objective measure versus questionnaire data for skin damage surrogates.

Main Methods:

  • Collected personal UVR dosimetry data, sun behavior diaries, and questionnaires from adults and children.
  • Defined intermittent UVR exposure as days exceeding 3x individual average daily UVR dose or individual constitutive skin type.
  • Used nevi and lentigines density as surrogates for CMM risk.

Main Results:

  • Identified 1241 intermittent days (7.2%) out of 17,277 total days among 148 participants using the dosimetry-based definition.
  • The number of intermittent days significantly predicted nevi and lentigo density (R(2)=0.15 and R(2)=0.40).
  • Retrospective questionnaire data showed lower prediction accuracy for nevi and lentigo density.

Conclusions:

  • Introduced a well-defined, objective measure for intermittent UVR exposure.
  • This objective measure demonstrates superior prediction of solar skin damage and CMM risk compared to retrospective questionnaire data.