Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Graded Potential

Graded Potential

Graded potentials are localized fluctuations in the cell membrane's electrical charge, commonly found in the dendrites of neurons. The magnitude of these potential changes depends on the strength of the initiating stimulus. In a membrane at its resting potential, a graded potential signifies a voltage shift either above -70 mV or below -70 mV.
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Decoding motor imagery related to major mimetic muscles from electroencephalography.

Journal of neuroengineering and rehabilitation·2026

Same author

Impacts of repetitive transcranial magnetic stimulation parameters on cerebral hemodynamics in patients with disorders of consciousness.

Frontiers in neurology·2026

Same author

Dopamine-sensitive dorsal striatal connectivity during short-video exposure is associated with addictive-like engagement traits.

Science bulletin·2026

Same author

Graph-Theoretical Signature from Neural and Vascular Signals Reveals Spinal Cord Stimulation Frequency-Specific Brain Network in Disorders of Consciousness Patients.

Cyborg and bionic systems (Washington, D.C.)·2026

Same author

Digital twin brain reveals state-specific stimulation targets for abnormal brain dynamics in tinnitus.

BMC medicine·2026

Same author

Cerebral Neurovascular Networks May Serve as Potential Targets for Identifying Disorders of Consciousness: A Synchronous Electroencephalography and Functional Near-Infrared Spectroscopy Study.

MedComm·2025

Search research articles

Related Experiment Video

Updated: Mar 16, 2026

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Published on: July 1, 2016

Correlation between electrical and hemodynamic responses during visual stimulation with graded contrasts.

Juanning Si¹, Xin Zhang¹, Yuejun Li²

¹Chinese Academy of Sciences, Brainnetome Center, Institute of Automation, Beijing 100190, ChinabChinese Academy of Sciences, National Laboratory of Pattern Recognition, Institute of Automation, Beijing 100190, China.

Journal of Biomedical Optics

|August 6, 2016

Summary

This study reveals that while visual evoked potential (VEP) amplitude correlates positively with hemodynamic response, VEP latency shows a negative correlation, offering new insights into visual processing.

More Related Videos

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Published on: June 9, 2015

Related Experiment Videos

Last Updated: Mar 16, 2026

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Simultaneous Recording of Electroretinography and Visual Evoked Potentials in Anesthetized Rats

Published on: July 1, 2016

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Stimulus-specific Cortical Visual Evoked Potential Morphological Patterns

Published on: May 12, 2019

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning

Published on: June 9, 2015

Area of Science:

Neuroscience
Biomedical Engineering
Cognitive Science

Background:

Brain activity involves complex interactions, making it challenging to study.
Multimodal neuroimaging combining electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) captures both electrical and blood-oxygen-level-dependent (BOLD) signals.
Visual evoked potential (VEP) amplitude is well-studied in relation to hemodynamic responses, but VEP latency's influence is less understood.

Purpose of the Study:

To investigate the relationship between VEP latency and hemodynamic responses.
To explore how VEP latency and amplitude differentially encode visual information.
To advance understanding of multimodal neuroimaging in visual processing.

Main Methods:

Utilized a multimodal neuroimaging approach combining EEG and fNIRS.
Employed checkerboard reversal tasks with varying contrasts to elicit visual functional activity.
Analyzed the correlation between VEP parameters (latency and amplitude) and hemodynamic responses.

Main Results:

VEP amplitudes demonstrated a linear correlation with the hemodynamic response.
VEP latency exhibited a negative linear correlation with the hemodynamic response.
Distinct relationships were observed between VEP amplitude, VEP latency, and hemodynamic activity.

Conclusions:

VEP latency provides unique information about hemodynamic responses, distinct from VEP amplitude.
This finding enhances the utility of multimodal neuroimaging for diagnosing visual impairments.
Understanding these relationships is crucial for interpreting complex brain activity in clinical and research settings.