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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Dermatofibrosarcoma protuberans post basal cell carcinoma excision: A case report.

Aaron M Mullane1, Alexis Ricci1, Subhasis Misra1

  • 1Texas Tech University Health Sciences Center, School of Medicine, Department of Surgery, 1400S, Coulter Street, Amarillo TX 79106, USA.

International Journal of Surgery Case Reports
|August 6, 2016
PubMed
Summary

Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. This case suggests a possible link between DFSP and basal cell carcinoma (BCC), highlighting the need for increased awareness and vigilance in diagnosis and treatment.

Keywords:
Basal cell carcinomaCD34Case reportDermatofibrosarcoma protuberansSarcoma

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Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, malignant dermal neoplasm.
  • Tumor recurrence is common and can be locally devastating.
  • DFSP can occur in surgical or burn scars.

Purpose of the Study:

  • To report a unique case of DFSP.
  • To investigate a potential association between DFSP and basal cell carcinoma (BCC).
  • To emphasize the need for increased awareness of DFSP among healthcare providers and patients.

Main Methods:

  • A case report of a 77-year-old male with a history of BCC excision.
  • Surgical excision of a palpable lesion on the abdominal wall.
  • Pathological examination revealing CD34-positive spindle cells consistent with DFSP.
  • Wide re-excision due to positive margins.

Main Results:

  • Pathology confirmed DFSP.
  • Initial resection margins were positive, requiring re-excision.
  • The lesion's location, less exposed to sun, suggested a possible association with prior BCC.

Conclusions:

  • An association between DFSP and BCC may exist, warranting further study.
  • Wide local excision with negative margins is crucial for DFSP treatment.
  • Increased physician awareness and vigilance can prevent morbidity associated with DFSP.