Related Experiment Video

Updated: Mar 16, 2026

Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
11:25

Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing

Published on: October 15, 2014

36.7K

Risk factors for mortality in patients with Stenotrophomonas maltophilia bacteremia

Yong Duk Jeon1, Woo Yong Jeong, Moo Hyun Kim

  • 1Department of Internal Medicine AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Medicine
|August 7, 2016
PubMed

Insights

Removing central venous catheters (CVCs) may significantly reduce mortality in patients with Stenotrophomonas maltophilia bacteremia. This finding is crucial for improving outcomes in critically ill patients with this nosocomial infection.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Hospital Epidemiology

Background:

  • Stenotrophomonas maltophilia is a significant nosocomial pathogen.
  • It is associated with high morbidity and mortality, especially in vulnerable patient populations.
  • Understanding mortality risk factors is crucial for clinical management.

Purpose of the Study:

  • To investigate risk factors for 28-day mortality in patients with S. maltophilia bacteremia.
  • To identify independent predictors of mortality in this patient cohort.
  • To inform clinical strategies for reducing S. maltophilia bacteremia mortality.

Main Methods:

  • Retrospective review of medical records for S. maltophilia bacteremia patients (2005-2014).
  • Inclusion of 142 patients from a tertiary care hospital.
  • Statistical analysis including univariate and multivariate logistic regression.

Main Results:

  • The overall 28-day mortality rate was 36.6%.
  • Multivariate analysis identified Sepsis-related Organ Failure Assessment (SOFA) score and central venous catheter (CVC) removal as independent predictors of mortality.
  • Removal of CVC was associated with reduced mortality (OR=0.330, P=0.049).

Conclusions:

  • Sepsis-related Organ Failure Assessment (SOFA) score is a significant predictor of mortality.
  • Removal of central venous catheters (CVCs) is a modifiable factor that can decrease mortality in S. maltophilia bacteremia.
  • Early CVC removal should be considered in the management of these patients.

More Related Videos

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

21.0K
A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model06:02

A Contemporary Warming/Restraining Device for Efficient Tail Vein Injections in a Murine Fungal Sepsis Model

Published on: November 6, 2020

18.3K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.5K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.2K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.1K
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
1.1K