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Wireless Recording in the Peripheral Nervous System with Ultrasonic Neural Dust.

Dongjin Seo1, Ryan M Neely2, Konlin Shen1

  • 1Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA 94720, USA.

Neuron
|August 7, 2016
PubMed
Summary

Researchers developed neural dust, a wireless ultrasonic system for bioelectronic medicine. This scalable technology powers and communicates with tiny implanted devices, offering a new way to record nerve signals.

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Area of Science:

  • Bioelectronic Medicine
  • Neuroscience
  • Biomedical Engineering

Background:

  • Current bioelectronic medicine interfaces face challenges with wires and scalability for small nerves.
  • Existing technologies lack high spatial resolution for recording nerve activity.

Purpose of the Study:

  • To introduce neural dust, a wireless ultrasonic backscatter system.
  • To demonstrate a scalable solution for powering and communicating with implanted bioelectronics.

Main Methods:

  • Utilized ultrasound for powering mm-scale devices in tissue.
  • Employed passive, battery-less ultrasonic backscatter for communication.
  • Recorded electromyogram (EMG) and electroneurogram (ENG) signals in anesthetized rats.

Main Results:

  • Ultrasound effectively delivered power to implanted devices.
  • High-fidelity EMG and ENG signal transmission was achieved wirelessly.
  • Demonstrated the potential of mm-scale, wireless bioelectronic interfaces.

Conclusions:

  • Neural dust offers a scalable, wireless solution for interfacing with peripheral nerves and muscles.
  • The technology advances bioelectronic medicine by enabling high-resolution neural recording.
  • This system holds promise for future bioelectronics-based therapies.