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Related Experiment Video

Updated: Mar 16, 2026

MPI CyberMotion Simulator: Implementation of a Novel Motion Simulator to Investigate Multisensory Path Integration in Three Dimensions

MPI CyberMotion Simulator: Implementation of a Novel Motion Simulator to Investigate Multisensory Path Integration in Three Dimensions

Published on: May 10, 2012

A touchscreen based global motion perception task for mice.

Jeffrey Stirman^1,2, Leah B Townsend³, Spencer Smith^1,2,3,4

¹Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Vision Research

|August 7, 2016

Summary

This summary is machine-generated.

Mice can perceive global motion using a novel touchscreen task. This study establishes a new method for studying visual perception in mice, crucial for understanding navigation.

Keywords:

Global motion processing Higher visual areas Psychophysics Random dot kinematograms Touchscreen chamber

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Area of Science:

Neuroscience
Visual System
Animal Behavior

Background:

Global motion perception relies on higher visual system circuits.
Mice exhibit adept visually driven navigation, but their global motion perception is not well understood.
Investigating global motion perception in mice is essential for understanding visual processing and navigation.

Purpose of the Study:

To develop and validate a touchscreen-based task for assessing global motion detection in mice.
To quantify global motion perception thresholds in mice using random dot kinematograms (RDK).
To establish an automated and high-throughput method for probing complex visual functions in mice.

Main Methods:

A two-alternative forced choice (2AFC) task was designed using a touchscreen interface.
Mice were trained to discriminate RDKs with varying motion directions.
Parameters such as dot size, lifetime, and speed were systematically tested.

Main Results:

Mice successfully learned to discriminate global motion direction within 7-24 days of training.
The average coherence threshold for global motion perception was determined to be 22±5%.
The developed touchscreen assay allowed for hundreds of trials per session with minimal experimenter intervention.

Conclusions:

Mice possess the capability for global motion discrimination.
The touchscreen-based 2AFC task is a viable and efficient method for studying visual perception in mice.
This assay facilitates high-throughput investigation of complex visual functions, aiding future neuroscience research.