ICU Management of the Potential Organ Donor: State of the Art
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Innovative Strategies for Organ Preservation in Heart Transplantation: Uniform Cooling Preservation and Ex-situ Normothermic Perfusion
Published on: November 28, 2025
Carolina B Maciel1, David M Greer2
1Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, P.O. Box 208018, New Haven, CT, 06520, USA.
Abstract:
End-organ failure is associated with high mortality and morbidity, in addition to increased health care costs. Organ transplantation is the only definitive treatment that can improve survival and quality of life in such patients; however, due to the persistent mismatch between organ supply and demand, waiting lists continue to grow across the world. Careful intensive care management of the potential organ donor with goal-directed therapy has the potential to optimize organ function and improve donation yield.
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