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Updated: Mar 16, 2026

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
Applying Data Mining Techniques to Improve Breast Cancer Diagnosis
Joana Diz1, Goreti Marreiros2, Alberto Freitas3,4
1CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal. joanamoreira.diz@gmail.com.
This study introduces a data mining approach to improve breast cancer diagnosis by classifying lesions and tissue density. Random Forests and Naive Bayes algorithms showed promising accuracy in identifying malignant/benign lesions and masses.
Area of Science:
- Medical Imaging
- Computational Biology
- Oncology
Background:
- Advanced computer-aided diagnosis systems are crucial for reducing false positives in breast cancer detection.
- Data mining offers a powerful approach to support oncologists in breast cancer classification and diagnosis.
Purpose of the Study:
- To compare two breast cancer datasets for improved diagnostic accuracy.
- To identify optimal data mining methods for predicting benign/malignant lesions, classifying breast density, and distinguishing between masses and microcalcifications.
Main Methods:
- Texture feature extraction using two matrices implemented in Matlab.
- Classification of extracted features using data mining algorithms within the WEKA software.
Main Results:
- Accuracies ranged from 89.3% to 64.7% for benign/malignant lesion prediction.
- Breast density classification achieved accuracies between 75.8% and 78.3%.
- Finding identification (mass/microcalcification) accuracies ranged from 71.0% to 83.1%.
Conclusions:
- Naive Bayes demonstrated superior performance in identifying mass textures.
- Random Forests proved to be a highly effective classifier for most tested breast cancer diagnostic tasks.
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