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Erratum to "Heterogeneous Sono-Fenton like catalytic degradation of metronidazole by Fe<sub>3</sub>O<sub>4</sub>@HZSM-5 magnetite nanocomposite" [Heliyon Volume 9, Issue 6, June 2023, Article e16461].

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A comparative study on the nanoparticles for improved drug delivery systems.

Nosrat O Mahmoodi1, Atefeh Ghavidast1, Najmeh Amirmahani2

  • 1Department of Chemistry, Faculty of Science, University of Guilan, P.O. Box 41335-1914, Rasht, Iran.

Journal of Photochemistry and Photobiology. B, Biology
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This review explores self-assembled nanoparticles for drug delivery systems (DDSs). Strategies focus on targeted drug placement and light-triggered release for enhanced cancer therapy.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Nanotechnology

Background:

  • Nanoparticles offer unique properties for biomedical applications.
  • Steric stabilization enhances nanoparticle stability in biological environments.
  • Surface ligand design is crucial for nanoparticle-based drug delivery systems (DDSs).

Purpose of the Study:

  • To review self-assembled nanoparticles for therapeutic applications.
  • To present strategies for improving drug targeting and controlled release.
  • To highlight the potential of light-triggered drug release.

Main Methods:

  • Surface modification of nanoparticles with specific ligands.
  • Conjugation of drugs or targeting moieties to DDS.
  • Utilizing external stimuli, specifically light, for controlled drug release.

Main Results:

  • Functionalized nanoparticles can interact with target molecules on cell membranes or intracellularly.
  • Two strategies for therapeutic nanoparticle design were presented.
  • Light offers spatiotemporal control over drug payload release.

Conclusions:

  • Self-assembled nanoparticles show promise for advanced drug delivery.
  • Targeted delivery and controlled release are key for effective cancer therapy.
  • Light-triggered systems provide precise control over therapeutic payload release.