The interface of depression and obesity
Nattinee Jantaratnotai1, Kanokwan Mosikanon2, Yena Lee3
1Department of Psychiatry, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Obesity Research & Clinical Practice
|August 9, 2016
Summary
Obesity and depression frequently co-occur, impacting public health. Treating one condition may improve outcomes for the other, suggesting integrated treatment approaches are beneficial.
Area of Science:
- Psychiatry
- Public Health
- Metabolic Disorders
Background:
- Depression and obesity are prevalent global health issues with significant impacts on morbidity, mortality, and healthcare costs.
- Epidemiological studies and meta-analyses confirm a strong association between mood disorders and obesity, with each being a risk factor for the other.
Purpose of the Study:
- To review the evidence on how obesity affects antidepressant response in depressive disorders.
- To examine if depressive disorders influence obesity progression and outcomes.
- To assess the impact of treating obesity on depressive disorder outcomes and vice versa.
Main Methods:
- Literature review focusing on studies meeting criteria for depressive disorders or obesity (BMI > 30).
- Evaluation of evidence addressing the bidirectional relationship and treatment interactions between depression and obesity.
Main Results:
- Obesity is associated with adverse health outcomes in individuals with depressive disorders.
- Evidence suggests that treating one condition (obesity or depression) can positively influence the course of the other.
Conclusions:
- Integrated treatment strategies addressing both obesity and depressive disorders are recommended.
- Screening for comorbid depression in obese patients and vice versa may improve patient outcomes.
Related Concept Videos
01:18Depression: Overview
1.1K
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
1.1K
01:24Obesity
1.5K
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.5K
01:27Depressive Disorders: Etiology
832
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
832
01:30Bulimia Nervosa
939
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
939
01:28Anorexia Nervosa
1.7K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
1.7K
01:27Depressive Disorders: MDD and Dysthymia
1.0K
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.0K