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Physiological Proteins in Therapeutics: A Current Review on Interferons
Debosree Ghosh, Debjani Ghosh, Pratap Parida1
1Centre for Studies in Biotechnology, Dibrugarh University, Assam, India. Pratap_parida2007@yahoo.com.
Interferons, crucial natural defense proteins, can be therapeutically adapted to combat viral diseases and cancers. Modified interferons, used with other drugs, offer enhanced protection against a wide range of illnesses.
Area of Science:
- Immunology
- Virology
- Biochemistry
Background:
- Interferons are key animal defense proteins released by virus-infected cells.
- They protect neighboring cells and have cyto-protective properties.
- Natural interferon production may be insufficient in certain diseases.
Purpose of the Study:
- To explore the pharmaceutical adaptation of interferons for therapeutic use.
- To investigate interferon's potential in treating viral diseases, cancer, and AIDS.
- To highlight the role of modified interferons in future disease management.
Main Methods:
- Review of existing research on interferon efficacy and applications.
- Discussion of interferon modification techniques (e.g., pegylation).
- Exploration of combination therapies involving interferons, antivirals, antibiotics, and antioxidants.
Main Results:
- Interferons exhibit therapeutic potential beyond viral infections, including cancer and AIDS.
- Modified interferons are already in clinical use for certain diseases.
- Combination therapies show promise for strengthening the immune defense system.
Conclusions:
- Interferon therapy, especially with modifications and in combination treatments, holds significant promise for combating viral threats and other diseases.
- Further development and application of interferons can contribute to disease-free living.
- Interferons are vital in strengthening the body's defense against a broad spectrum of illnesses.
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