[Correlations between clinico-functional and computerized tomography parameters in patients with optic atrophy of...

Comprehensive examinations of the optic nerve anatomy and function in atrophies of various origins have revealed a correlation between computerized tomography data and clinical and functional characteristics in 67 patients. A staged pattern of the development of anatomic shifts corresponding to CT data on the changes in the optic nerve diameter and density in accord with the length of the disease has been determined, as well as a relationship between these shifts and the patients' age and the degree of the calcification of the internal carotid arterial walls. CT signs of the optic nerve atrophy are related to functional disorders. Impaired circulation in the internal carotid arteries augments the atrophic process in the optic nerve. These data may be useful for the selection of a method for the management of optic nerve atrophy and for assessment of the treatment efficacy.