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Updated: Mar 16, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
39.6K
Recent advances in phototherapy for psoriasis
Mio Nakamura1, Benjamin Farahnik2, Tina Bhutani1
1Department of Dermatology, University of California San Francisco Psoriasis and Skin Treatment Center, San Francisco, California, USA.
F1000Research
|August 9, 2016
Summary
Phototherapy, using ultraviolet light, effectively treats psoriasis by targeting immune responses. Advancements like excimer lasers and combination therapies offer new hope for long-lasting psoriasis remission.
Area of Science:
- Dermatology
- Immunology
- Photomedicine
Background:
- Phototherapy utilizes ultraviolet light for treating inflammatory skin conditions like psoriasis.
- Emerging research highlights the immunologic mechanisms behind phototherapy's effectiveness.
- Psoriasis treatment has seen advancements in targeted phototherapy for challenging areas.
Purpose of the Study:
- To review the efficacy and advancements in phototherapy for psoriasis.
- To explore the immunologic effects contributing to phototherapy's success.
- To discuss novel phototherapy modalities and combination treatments for psoriasis.
Main Methods:
- Review of recent studies on phototherapy for psoriasis.
- Analysis of immunologic mechanisms of phototherapy.
- Evaluation of targeted phototherapy (excimer laser) and combination therapy with biologics.
Main Results:
- Phototherapy demonstrates significant efficacy in treating psoriasis through immunomodulation.
- Targeted phototherapy, such as excimer laser, shows promise for difficult-to-treat psoriasis.
- Combination therapy with biologics enhances treatment outcomes for recalcitrant psoriasis.
Conclusions:
- Phototherapy remains a crucial treatment for psoriasis, despite being an established modality.
- Ongoing advancements in phototherapy offer improved efficacy and remission potential.
- Targeted and combination phototherapy approaches represent promising future directions for psoriasis management.
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