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Related Concept Videos

Hand hygiene01:23

Hand hygiene

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
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Related Experiment Video

Updated: Mar 16, 2026

Povidone Iodine Rectal Preparation at Time of Prostate Needle Biopsy is a Simple and Reproducible Means to Reduce Risk of Procedural Infection
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Probable glucometer interference caused by topical iodine solution test site preparation.

A M Lipshutz1, E M Hawes2,3,4

  • 1Department of Pharmacy, Mount Carmel West Hospital, Columbus, OH, USA.

Journal of Clinical Pharmacy and Therapeutics
|August 9, 2016
PubMed
Summary

Povidone-iodine skin preparation can interfere with modern glucometers, causing inaccurate blood glucose readings. Always ensure proper hand hygiene before testing to obtain reliable glucose measurements.

Keywords:
ambulatory caredisinfectantgestational diabetesglucose testingiodine

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Area of Science:

  • Clinical Chemistry
  • Medical Devices
  • Point-of-Care Testing

Background:

  • Skin disinfection is standard practice before blood glucose monitoring.
  • Previous studies indicated that certain disinfectants could affect glucose meter accuracy.

Observation:

  • A case study involving a pregnant woman highlighted significant glucose meter inaccuracies.
  • The inaccuracies were linked to the use of 10% povidone-iodine solution for skin preparation.

Findings:

  • Topical iodine likely caused variable and erroneous blood glucose readings.
  • Replacing iodine with hand washing resolved the issue, confirming a probable drug-device interaction.

Implications:

  • This interaction can occur with current electrochemical glucometers.
  • Clinicians should consider improper testing techniques, including disinfectant use, when encountering aberrant glucose readings.