Related Experiment Video
Updated: Mar 16, 2026
11:05
SECONDs Administration Guidelines: A Fast Tool to Assess Consciousness in Brain-injured Patients
Published on: February 6, 2021
17.3K
[Wernicke-Korsakoff syndrome]
S V Kotov1, A I Lobakov1, E V Isakova1
1M.F. Vladimirski Moscow Regional Research Institute, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|August 9, 2016
Summary
Non-alcoholic Wernicke-Korsakoff syndrome (WKS) in gastrointestinal disease patients requires prompt thiamine treatment. Early diagnosis and vitamin B therapy can prevent severe cognitive deficits.
Area of Science:
- Neurology
- Gastroenterology
- Nutritional Science
Background:
- Non-alcoholic Wernicke-Korsakoff syndrome (WKS) is a serious neurological complication.
- Gastrointestinal tract (GIT) diseases, malabsorption, and upper GIT surgery increase WKS risk.
Purpose of the Study:
- To investigate the diagnosis and treatment of non-alcoholic Wernicke-Korsakoff syndrome (WKS).
Main Methods:
- Study included eight patients with WKS linked to GIT disease, malabsorption, or post-surgery.
- Clinical manifestations, MRI findings, and treatment responses were analyzed.
Main Results:
- Patients presented with consciousness disturbance, ataxia, eye movement disorders, and bulbar syndrome within 24-48 hours.
- MRI showed characteristic brain lesions in the hypothalamus, mamillary bodies, brain stem, and hippocampus.
- Treatment with vitamin B complex and thiamine demonstrated a positive therapeutic effect.
Conclusions:
- Patients with GIT disease and malabsorption are identified as a high-risk group for WKS.
- Prompt recognition of neurological symptoms and initiation of thiamine treatment are crucial.
- Timely thiamine administration can prevent the development of irreversible cognitive deficits.
Related Concept Videos
01:10Higher Mental Functions of the Brain: Language
4.0K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
4.0K
01:13Amnesia
740
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
740
01:24Chronic Kidney Disease II: Clinical Manifestations
880
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
880
01:12Visual Agnosia
1.6K
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
1.6K
01:30Dementia
660
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
660
01:21Dissociative Amnesia
855
Dissociative amnesia is a complex psychological condition that manifests as an inability to recall personal information, often tied to traumatic or stressful events. Unlike general amnesia, individuals with this condition retain the ability to perform routine activities and procedural tasks, such as operating a phone or navigating public transportation, yet experience profound gaps in autobiographical memory. These lapses may encompass significant life events, such as suicide attempts or...
855