Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

998
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
998

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative Ultrasound Imaging of Bone: Anatomical Images, Tissue Structural Quality, and Pulsatile Blood Flow.

IEEE transactions on medical imaging·2026
Same author

t(11;14) multiple myeloma patient: minimal residual disease after 10 years of follow-up - a case report.

Haematologica·2025
Same author

Perisplenic fibrosis.

European journal of internal medicine·2025
Same author

Functional patterns of healthy human respiratory dynamics by 3D MR spirometry.

European radiology·2025
Same author

Pictorial review of bilateral adnexal lesions.

Abdominal radiology (New York)·2025
Same author

Non selective beta-blockers prevent PHT-related complications occurrence in HCC patients with esophageal varices treated by TACE.

Clinics and research in hepatology and gastroenterology·2024

Related Experiment Video

Updated: Mar 16, 2026

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy
10:10

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Published on: July 20, 2022

4.8K

Does motion affect liver stiffness estimates in shear wave elastography? Phantom and clinical study.

Claire Pellot-Barakat1, Linda Chami2, Jean Michel Correas3

  • 1Laboratoire Imagerie Moléculaire In Vivo (IMIV), UMR 1023 Inserm/CEA/Université Paris Sud - ERL 9218 CNRS, CEA/I2BM/SHFJ, Orsay, France.

European Journal of Radiology
|August 10, 2016
PubMed
Summary

Free-breathing (FB) shear-wave elastography (SWE) measurements correlate with apnea but show lower liver stiffness values and degraded data quality. Patient breath-holding, not mechanical motion, likely causes these discrepancies.

Keywords:
ApneaElasticityFeasibilityFibrosisRespirationUltrasound imaging

More Related Videos

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
07:13

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Published on: April 20, 2021

4.6K
Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI
06:09

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI

Published on: July 21, 2023

2.0K

Related Experiment Videos

Last Updated: Mar 16, 2026

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy
10:10

Measurement of Liver Stiffness Using Atomic Force Microscopy Coupled with Polarization Microscopy

Published on: July 20, 2022

4.8K
Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
07:13

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Published on: April 20, 2021

4.6K
Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI
06:09

Author Spotlight: Advancing Hepatic Fibrosis Diagnosis Using Magnetic Resonance Elastography and AI

Published on: July 21, 2023

2.0K

Area of Science:

  • Medical Imaging
  • Hepatology
  • Biophysics

Background:

  • Shear-wave elastography (SWE) is a non-invasive method for assessing liver stiffness.
  • Breath-holding techniques (apnea) are commonly used to improve SWE measurement quality.
  • The impact of free-breathing (FB) versus apnea on SWE measurements requires further investigation.

Purpose of the Study:

  • To compare liver stiffness measurements obtained using free-breathing (FB) and apnea techniques in shear-wave elastography (SWE).
  • To evaluate the influence of patient body morphology and liver texture on the accuracy and reliability of FB and apnea SWE measurements.
  • To assess the quality of elasticity maps generated during FB and apnea using metrics like percentage of non-filling (PNF) and temporal (TV) and spatial (SV) variabilities.

Main Methods:

  • Quantitative liver stiffness measurements were performed using SWE on 97 patients during both FB and apnea.
  • Quality indexes including PNF, TV, and SV were computed for elasticity maps from both breathing conditions.
  • SWE measurements were also validated using an homogeneous phantom under static and motion conditions.

Main Results:

  • Liver stiffness values from FB and apnea SWE were highly correlated (r=0.76 for homogeneous livers, r=0.68 for favorable body morphologies).
  • FB measurements consistently yielded 20-25% lower stiffness values compared to apnea (P<0.001).
  • FB resulted in degraded TV (P<0.005) and PNF (P<0.001) but did not affect SV, indicating reduced data quality.

Conclusions:

  • While FB and apnea SWE measurements are correlated, FB leads to systematically lower stiffness values and poorer data quality.
  • Discrepancies observed in patients but not in phantoms suggest that patient breath-holding significantly impacts liver stiffness measurements.
  • Apnea remains a more reliable method for accurate liver stiffness assessment using SWE, especially in diverse patient populations.