Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Upper GI Series: Barium Swallow

Upper GI Series: Barium Swallow

The Barium Swallow Study, or a Barium Esophagogram, is a diagnostic imaging method used to visualize the upper gastrointestinal (GI) tract, including the esophagus, stomach, and small intestine. It employs barium sulfate, a radiopaque contrast material, to provide clear images of the upper digestive system, helping to identify abnormalities, diseases, or structural issues.
Purpose and Procedure
Patients undergoing this procedure ingest a liquid containing barium sulfate with a chalky...

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...

Assessment of the Rectum and Anus

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

ESR1 overexpression is a biomarker of relapse and worse prognosis in stage I endometrioid endometrial carcinoma.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2025

Same author

Prognostic factors associated with overall survival in patients with oral cavity squamous cell carcinoma.

Medicina oral, patologia oral y cirugia bucal·2020

Same author

Towards low-cost QEPAS sensors for nitrogen dioxide detection.

Photoacoustics·2020

Same author

New effects of caffeine on corticotropin-releasing hormone (CRH)-induced stress along the intrafollicular classical hypothalamic-pituitary-adrenal (HPA) axis (CRH-R1/2, IP<sub>3</sub> -R, ACTH, MC-R2) and the neurogenic non-HPA axis (substance P, p75<sup>NTR</sup> and TrkA) in ex vivo human male androgenetic scalp hair follicles.

The British journal of dermatology·2020

Same author

Quality of life after total laryngectomy: impact of different vocal rehabilitation methods in a middle income country.

Health and quality of life outcomes·2020

Same author

Framework for personalized prediction of treatment response in relapsing remitting multiple sclerosis.

BMC medical research methodology·2020

Same journal

["DOG 2020 online" - for the first time in the von Graefe year].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2024

Same journal

[Are organ and co-cultures an alternative to animal models in ophthalmology?]

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2022

Same journal

[Pediatric corneal opacities : Even small improvements provide lifelong help].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2022

Same journal

[Myxoma of the conjunctiva].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2022

Same journal

[Secondary open-angle glaucoma: uveitic secondary glaucoma, steroid-induced glaucoma, posttraumatic and postoperative glaucoma, tumor-related glaucoma and glaucoma due to elevated episcleral venous pressure].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2022

Same journal

[Artificial intelligence in the management of anti-VEGF treatment: the Vienna fluid monitor in clinical practice].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2022

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 16, 2026

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards

Published on: September 3, 2020

[Extensive yellowish fundus changes in a 6-year-old child].

S Gottwalt¹, A Bergmann², M Kautza-Lucht²

¹Universitätsaugenklinik, UKSH Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland. stefan.gottwalt@uksh.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|August 10, 2016

Summary

This summary is machine-generated.

Molecular genetics diagnosed autosomal recessive bestrophinopathy (ARB) in a young girl with vision loss. Over 22 months, she showed slight visual recovery and reduced subretinal deposits.

Keywords:

Autosomal recessive bestrophinopathy (ARB)BEST1 Intraretinal cysts Molecular genetics Yellowish subretinal deposits

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Mar 16, 2026

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards

Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards

Published on: September 3, 2020

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Author Spotlight: Understanding Age-Related Macular Degeneration Pathophysiology with QAF Workflow

Published on: May 26, 2023

Area of Science:

Ophthalmology
Medical Genetics
Retinal Diseases

Background:

Autosomal recessive bestrophinopathy (ARB) is a rare inherited retinal disorder.
Early diagnosis is crucial for managing potential vision impairment.

Observation:

A 6-year-old girl presented with best corrected visual acuity of 0.6 in both eyes.
Clinical examination revealed yellowish subretinal lesions in the macula and around the vessel arcade.
Angiography showed no signs of vasculitis or abnormal vessels; fundus autofluorescence was marked, and SD-OCT revealed subretinal hyperreflective masses.

Findings:

Molecular genetics confirmed the diagnosis of autosomal recessive bestrophinopathy (ARB).
Over a 22-month follow-up, the patient exhibited a slight improvement in visual acuity.
A reduction in subretinal deposits was also observed during the follow-up period.

Implications:

This case highlights the utility of molecular genetics in diagnosing ARB.
The findings suggest a potential for visual recovery and reduction of lesions in ARB patients.
Further research into the natural history and treatment of ARB is warranted.