Related Experiment Video
Updated: Mar 16, 2026

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Rare case of gallbladder agenesis presenting with pancreatitis
Luke Thornton1, Yan Li Goh1, Mark Lipton1
1Arrowe Park Hospital, Merseyside, UK.
Insights
Gallbladder agenesis (GA), a rare congenital condition, can present with pancreatitis. This case highlights the potential coexistence of biliary and pancreatic pathologies in GA patients.
Area of Science:
- Gastroenterology
- Congenital Abnormalities
- Biliary System Research
Background:
- Gallbladder agenesis (GA) is a rare congenital condition with an incidence of 0.01-0.09%.
- While often isolated, GA can be associated with various systemic malformations.
- Coexistence of biliary and pancreatic pathologies is suspected in GA.
Observation:
- This report details a second documented case of gallbladder agenesis presenting with pancreatitis.
- The patient's presentation involved complications typically associated with biliary and pancreatic system interactions.
Findings:
- The study confirms the rare association between gallbladder agenesis and pancreatitis.
- This case underscores the importance of considering pancreatic involvement in patients with GA.
Implications:
- Highlights the need for comprehensive diagnostic evaluation in patients with gallbladder agenesis.
- Contributes to understanding the spectrum of complications associated with congenital biliary tract anomalies.
- Informs clinical management strategies for rare congenital gallbladder abnormalities and associated pathologies.
Abstract:
Gallbladder agenesis (GA) is a rare congenital abnormality with an incidence of 0.01-0.09%. Majority of GA exist alone although it can be associated with other systemic malformations involving the gastrointestinal, genitourinary, cardiovascular and skeletal systems. It is thought that biliary and pancreatic pathologies coexist and this is the second case reported in the literature of GA presenting with pancreatitis.
Related Concept Videos
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis II: Collaborative Care
Assessment:
Gallbladder
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...

