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Brown Heroin-Associated Candida albicans Ventriculitis and Endophthalmitis Treated with Voriconazole

Nora Elfiky1, Kelly Baldwin1

  • 1Geisinger Medical Center, Department of Neurology, Danville, Pa., USA.

Case Reports in Neurology
|August 10, 2016
PubMed

Insights

Chronic meningitis and ventriculitis, persistent brain inflammation, can lead to vision loss. This case highlights Candida albicans infection secondary to brown heroin use, causing ventriculitis and endophthalmitis.

Area of Science:

  • Neurology
  • Ophthalmology
  • Infectious Diseases

Background:

  • Chronic meningitis and ventriculitis involve persistent cerebrospinal fluid (CSF) inflammation lasting over a month.
  • The brain's CSF system connects to the eye, making fungal brain infections a risk for secondary ocular complications.

Observation:

  • A 23-year-old male presented with severe headaches and progressive monocular vision loss.
  • The patient was diagnosed with ventriculitis and endogenous endophthalmitis.

Findings:

  • The patient's condition was linked to brown heroin use.
  • Disseminated Candida albicans infection was suspected as the etiology.

Implications:

  • This case underscores the severe neurological and ophthalmological risks associated with intravenous drug use.
  • Early diagnosis and multidisciplinary management are crucial for treating fungal infections affecting the central nervous system and eyes.
Keywords:
Brown heroinCandida albicansChronic meningitisEndopthalmitisFungal meningitisVentriculitis

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