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Life Course Socioeconomic Transition and its Association with Early Onset Type 2 Diabetes: Protocol for a Sequential
Sankar Vadassery Uma1, V Kutty Raman2, Santhosh Kumar Nochikattil3
1PhD Scholar, Achutha Menon Centre for Health Sciences Studies, Sree Chitra Tirunal Institute for Medical Science & Technology (SCTIMST) , Trivandrum, Kerala, India .
Individuals with lower childhood socioeconomic position (SEP) and higher adult SEP face increased risk for early-onset type 2 diabetes. This study developed a validated questionnaire to assess life course socioeconomic transition (LSET) and its association with diabetes.
Area of Science:
- Epidemiology
- Public Health
- Socioeconomic Determinants of Health
Background:
- Rising global prevalence of early-onset type 2 diabetes (T2D) in individuals under 45 years.
- Life Course Socio-Economic Transition (LSET) may influence T2D development through economic, occupational, and lifestyle factors.
Purpose of the Study:
- To develop and validate a questionnaire for measuring LSET.
- To investigate the association between LSET and early-onset T2D.
Main Methods:
- Sequential exploratory mixed-methods study design.
- Qualitative interviews to develop the LSET questionnaire.
- Quantitative validation through cross-sectional survey (n=200) and hospital-based case-control study.
Main Results:
- Individuals experiencing a transition from lower childhood SEP to higher adulthood SEP showed an increased risk of developing T2D at a younger age (18-45 years).
Conclusions:
- A validated LSET questionnaire was developed.
- The study provides a tool for epidemiological research on LSET and early-onset T2D.
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