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Parathyroid Adenoma Completely Impacted within the Thyroid Gland: A Case Report
Sayed Mahmoud Mirhosaini1, Soroush Amani2, Rana Fereidani3
1Assistant Professor, Department of Internal Medicine, Hajar Hospital, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Journal of Clinical and Diagnostic Research : JCDR
|August 10, 2016
Summary
Ectopic parathyroid adenoma can mimic thyroid nodules, complicating diagnosis. Immunohistochemistry confirmed parathyroid adenoma in a patient whose fine needle aspiration was suspicious for a thyroid neoplasm.
Area of Science:
- Endocrinology
- Surgical Pathology
- Diagnostic Imaging
Background:
- Ectopic parathyroid adenomas present diagnostic challenges, often mimicking thyroid lesions on imaging and fine needle aspiration.
- Distinguishing parathyroid adenomas from thyroid nodules requires definitive histopathological and immunohistochemical analysis.
Observation:
- A 29-year-old woman presented with a left thyroid lobe nodule, initially evaluated with normal thyroid function tests.
- Ultrasonography identified a 25x20 mm hypoechoic mass in the inferior left thyroid lobe.
- Fine needle aspiration was suspicious for a follicular neoplasm, prompting further investigation.
Findings:
- Immunohistochemistry, utilizing a parathyroid hormone (PTH) marker, confirmed the presence of parathyroid adenoma.
- Postoperative histopathology and immunohistochemistry definitively diagnosed parathyroid adenoma, differentiating it from a suspected thyroid neoplasm.
Implications:
- This case highlights the importance of immunohistochemistry in diagnosing ectopic parathyroid adenoma, especially when it presents as a thyroid nodule.
- Ultrasonography can aid in localizing thyroid lesions, but definitive diagnosis of parathyroid adenoma requires specific markers.
