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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
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Other Pulmonary Disorders01:17

Other Pulmonary Disorders

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Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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COPD: Pathogenesis and Clinical Features01:20

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Pulmonary Hypertension: Classification and Pathogenesis01:30

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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
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Systemic Sclerosis with Multiple Pulmonary Manifestations.

Mohan Rao Kotnur1, Parinita Suresh2, Venkata Siva Prasad Reddy2

  • 1Professor and Head, Department of Respiratory Medicine, Rajarajeswari Medical College and Hospital , Bangalore, India .

Journal of Clinical and Diagnostic Research : JCDR
|August 10, 2016
PubMed
Summary
This summary is machine-generated.

Systemic sclerosis (SSc) is an autoimmune disease causing fibrosis. This case highlights uncommon lung issues in SSc, including interstitial lung disease with a usual interstitial pneumonia pattern, pulmonary arterial hypertension, and pleural effusion.

Keywords:
Interstitial lung diseasePulmonary arterial hypertensionSclerodermaUsual interstitial pneumonia

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Area of Science:

  • Rheumatology
  • Pulmonology
  • Internal Medicine

Background:

  • Systemic sclerosis (SSc) is a chronic autoimmune disease affecting multiple organs.
  • It is characterized by endothelial and fibroblast dysfunction, leading to fibrosis.
  • Pulmonary complications, including Interstitial Lung Disease (ILD) and Pulmonary Arterial Hypertension (PAH), are major causes of mortality in SSc patients.

Observation:

  • This report details a case of an elderly female patient diagnosed with diffuse Systemic Sclerosis.
  • The patient presented with several uncommon pulmonary manifestations.
  • These included ILD exhibiting a Usual Interstitial Pneumonia (UIP) pattern, PAH, and a right-sided pleural effusion.

Findings:

  • The case demonstrates the potential for diverse and less common pulmonary involvement in Systemic Sclerosis.
  • The presence of ILD with a UIP pattern, typically less frequent in SSc, was noted.
  • Co-occurrence of PAH and pleural effusion further emphasizes the complex pulmonary sequelae.

Implications:

  • This case underscores the importance of vigilant monitoring for varied pulmonary manifestations in SSc patients.
  • Recognizing uncommon patterns like UIP in SSc-ILD can aid in timely diagnosis and management.
  • Further research into the specific mechanisms driving these diverse pulmonary involvements in SSc is warranted.