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Related Concept Videos

Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
836
REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

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REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
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Nephrons01:10

Nephrons

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The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
8.2K
Antihypertensive Drugs: Potassium-Sparing Diuretics01:28

Antihypertensive Drugs: Potassium-Sparing Diuretics

2.6K
Liddle syndrome is a genetically inherited form of hypertension characterized by the overactivity of epithelial sodium channels in the nephron, the functional unit of the kidney. This heightened activity leads to increased sodium reabsorption and excessive excretion of potassium. To counteract this, potassium-sparing diuretics such as amiloride are used. They function by blocking these sodium channels, thereby reducing the influx of sodium into the epithelial cells and minimizing the loss of...
2.6K
Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

295
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
295
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

417
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
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Evaluation of Zebrafish Kidney Function Using a Fluorescent Clearance Assay
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Bednar Tumor: An Uncommon Entity.

Gayathri P Amonkar1, Asha Rupani1, Ajay Shah1

  • 1Department of Pathology, T.N. Medical College and B.Y.L. Nair Hospital, Mumbai, India.

Dermatopathology (Basel, Switzerland)
|August 10, 2016
PubMed
Summary
This summary is machine-generated.

Bednar tumor, a rare pigmented variant of dermatofibrosarcoma protuberans, is an intermediate-grade tumor typically affecting adults. This case highlights the importance of considering this diagnosis in pigmented spindle cell lesions.

Keywords:
Bednar tumorDifferentiationPigmented dermatofibrosarcoma protuberans

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Area of Science:

  • Dermatopathology
  • Oncology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive skin cancer.
  • Bednar tumor is an uncommon pigmented variant of DFSP, characterized by pseudo-epitheliomatous hyperplasia and spindle cells with melanin.

Observation:

  • A rare case of Bednar tumor is presented in a 40-year-old female patient.
  • The tumor presented as a pigmented subcutaneous lesion.

Findings:

  • Bednar tumor is an intermediate-grade malignancy.
  • Histopathological examination is crucial for diagnosis, revealing characteristic spindle cells and melanin pigment.

Implications:

  • The diagnosis of Bednar tumor should be considered in cases of pigmented subcutaneous spindle cell lesions.
  • Early recognition and diagnosis are vital for appropriate management of this rare tumor.