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Severe microvascular disease in type II diabetes of early onset. A family study
T Scalvini1, S Spandrio, O di Stefano
1Cattedra di Patologia Medica, Università di Brescia, II Divisione di Medicina, Spedali di Brescia, Italy.
Acta Diabetologica Latina
|January 1, 1989
Abstract:
Both early onset and late onset type II diabetes were present in one family of nine siblings. The three early onset type II diabetic siblings showed severe microvascular complications: proliferative retinopathy, diabetic nephropathy, and peripheral neuropathy. Early onset type II diabetes was not associated with any particular HLA haplotype. Early onset type II diabetes could be considered a clinical and genetic disease entity different from MODY type diabetes.