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Spindle Cell Sarcoma Presenting as Pancoast Syndrome.

Aliena Badshah¹, Salman Khan¹, Usman Saeed¹

¹Department of Medicine, Khyber Teaching Hospital, Peshawar.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|August 10, 2016

Summary

This case report details a rare instance of spindle cell sarcoma in the lung presenting as Pancoast syndrome. This aggressive tumor required radiotherapy due to its advanced stage and surgical non-resectability.

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Area of Science:

Pulmonology
Oncology
Pathology

Background:

Spindle cell sarcoma is a rare, rapidly replicating connective tissue tumor.
Pancoast syndrome is characterized by specific neurological and vascular symptoms in the upper thorax.

Observation:

A 56-year-old male presented with dyspnea, neck vein engorgement, upper limb edema, ptosis, miosis, and right ulnar nerve palsy.
Imaging revealed a right upper lobe lung mass, mediastinal widening, bilateral pleural effusion, and pericardial effusion.

Findings:

Bronchoscopic biopsy confirmed spindle cell sarcoma of the lung.
The tumor involved mediastinal lymph nodes, pleura, and pericardium, rendering it unresectable.

Implications:

This case highlights the first reported instance of spindle cell sarcoma of the lung manifesting as Pancoast syndrome.
Early diagnosis and multimodal treatment approaches are crucial for managing rare lung malignancies.
Further research into the pathogenesis and treatment of spindle cell sarcomas is warranted.