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Palatine bone in human cyclopia.

P McGrath1

  • 1Department of Anatomy, University of Sydney, Australia.

Acta Anatomica
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Human cyclopia involves a maxillopalatine mass. This study details the palatine bone

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Area of Science:

  • Medical Science
  • Developmental Biology
  • Human Anatomy

Background:

  • Human cyclopia is a rare congenital disorder characterized by the fusion of the orbits.
  • A distinctive feature is the presence of a maxillopalatine mass.
  • This mass separates the median orbit from the oral cavity.

Purpose of the Study:

  • To investigate the palatine component of the maxillopalatine mass in human cyclopia.
  • To analyze the detailed morphology and anatomical relationships of the palatine bone in affected specimens.

Main Methods:

  • Serial sectioning of three perinatal human heads with cyclopia.
  • Sagittal and coronal plane sectioning for detailed anatomical analysis.
  • Identification of palatine bone structures using neurovascular bundles (maxillary artery and nerve).

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Main Results:

  • Detailed description of the palatine component of the maxillopalatine mass.
  • Reconstruction of the palatine bone's presentation on a dried cyclops skull.
  • Identification of the course and relationships of maxillary neurovascular bundles.

Conclusions:

  • Abnormalities of the palatine bone in human cyclopia may be secondary to developmental defects.
  • The absence of the presphenoid bone and nasal cavity are implicated in palatine bone abnormalities.
  • This study provides insights into the craniofacial developmental anomalies in cyclopia.