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Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients
Emre Özgü1, Murat Öz, Yunus Yıldız
1Zekai Tahir Burak Women Health Education and Research Hospital, Gynecologic Oncology Department, Ankara, Turkey. emreozgu@hotmail.com.
Objectives:
To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.
Material And Methods:
We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative ¹⁸F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.
Results:
The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III-IV compared with stage I-II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.
Conclusions:
PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.
