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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Positron Emission Tomography01:29

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
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X-ray Imaging01:24

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German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
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Total Internal Reflection Fluorescence Microscopy01:05

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
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Related Experiment Video

Updated: Mar 16, 2026

Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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Snapshot fan beam coded aperture coherent scatter tomography.

Mehadi Hassan, Joel A Greenberg, Ikenna Odinaka

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    |August 10, 2016
    PubMed
    Summary

    This study introduces a novel X-ray imaging technique for volumetric molecular composition analysis. The method achieves high resolution and a 100x speedup, enabling comprehensive 4D imaging.

    Area of Science:

    • Physics
    • Materials Science
    • Imaging Technology

    Background:

    • Accurate molecular composition measurement is crucial for material analysis.
    • Previous X-ray techniques faced limitations in speed and volumetric imaging.
    • Coherently scattered X-rays offer potential for advanced material characterization.

    Purpose of the Study:

    • To develop and validate a new X-ray imaging method for volumetric molecular composition.
    • To assess the resolution and speed improvements of the proposed technique.
    • To demonstrate the capability for full 4D data cube acquisition.

    Main Methods:

    • Utilizing coherently scattered X-rays with a fan beam illumination.
    • Employing a coded aperture between the object and detectors for planar slice imaging.

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  • Characterizing system performance including resolution and momentum transfer.
  • Scanning the object to acquire a 4-dimensional data cube.
  • Main Results:

    • Achieved a spatial resolution of 13 mm in range and 2 mm in cross-range.
    • Demonstrated a fractional momentum transfer resolution of 15%.
    • Showcased a 100x speedup compared to previous pencil beam systems.
    • Successfully imaged a 4D data cube (3 spatial, 1 material dimension).

    Conclusions:

    • The developed X-ray technique enables efficient volumetric molecular imaging.
    • The system offers significant improvements in speed and resolution.
    • This method provides a pathway for complete material characterization.