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Effective axillary malodour reduction by polyquaternium-16-containing deodorants.

B Traupe1, H Fölster1, H Max1

  • 1Research & Development, Beiersdorf AG, Unnastrasse 48, 20245, Hamburg, Germany.

International Journal of Cosmetic Science
|August 11, 2016
PubMed
Summary

A new deodorant with polyquaternium-16 (PQ-16) effectively reduced underarm odor and bacteria. This PQ-16 formulation outperformed a leading commercial deodorant in a 48-hour study.

Keywords:
deodorantemulsionsmicrobiologypolymerspolyquaternium-16

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Area of Science:

  • Dermatology
  • Microbiology
  • Cosmetic Science

Background:

  • Axillary malodour is a common concern addressed by topical deodorants.
  • There is a continuous demand for effective and safe deodorant actives.
  • Polymeric quaternary ammonium compounds (PQ-16) are investigated as potential antimicrobial agents.

Purpose of the Study:

  • To evaluate the antimicrobial effectiveness of a novel polymeric quaternary ammonium compound (PQ-16) in a roll-on deodorant formulation.
  • To compare the efficacy of the PQ-16 deodorant against a commercial benchmark and a control formulation.
  • To assess the impact on axillary microbial growth and malodour intensity.

Main Methods:

  • In vivo microbiological assessment of bacterial counts.
  • Comparison of PQ-16 deodorant (DEO1) against a commercial deodorant (DEO2) and an aluminum chlorohydrate control (DEO3).
  • Sensory evaluation of axillary malodour by a trained panel at 24 and 48 hours post-application.

Main Results:

  • DEO1 significantly reduced bacterial counts compared to DEO2 at all time points.
  • Malodour intensity was significantly lower with DEO1 versus DEO2 at 24 and 48 hours.
  • DEO1 showed comparable results to DEO3 in bacterial counts and malodour at 48 hours.

Conclusions:

  • Polyquaternium-16 (PQ-16) is a highly effective deodorant active ingredient.
  • The PQ-16 roll-on formulation demonstrated significant reduction in axillary malodour and bacteria.
  • PQ-16 offers an innovative, skin-friendly alternative for deodorant applications.