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Updated: Mar 16, 2026
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Treatment of common pediatric CNS malignancies with proton therapy
Arpit Chhabra1, Anita Mahajan2
1Department of Radiation Oncology, The University of Maryland School of Medicine, Baltimore, Maryland, USA.
Abstract:
Radiation therapy plays an important role in the management of pediatric CNS malignancies. With the improving outcomes of these patients, the potential risk of late toxicities present with current radiation therapy techniques (i.e., 3D-CRT, IMRT, VMAT) has become apparent. Proton therapy (PRT), due to its unique physical characteristics, provides an advantage in reducing unintended dose to normal tissue structures, and the resultant acute and late side effects of this dose "bath". In this review we will highlight the current standards of care, and the benefits achieved with using PRT in treating common childhood CNS tumors.
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