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Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Autoimmune Disorders01:29

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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Related Experiment Video

Updated: Mar 16, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

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[Systemic lupus erythematosus and pregnancy].

Karen Schreiber1, Jacob Alexander Lykke, Henriette Svarre Nielsen

  • 1sj@dadlnet.dk.

Ugeskrift for Laeger
|August 11, 2016
PubMed
Summary

Systemic lupus erythematosus (SLE) in pregnant women requires careful management. Joint care by multidisciplinary teams improves outcomes for both mother and child.

Area of Science:

  • Rheumatology
  • Obstetrics
  • Autoimmune Diseases

Background:

  • Systemic lupus erythematosus (SLE) primarily affects women of childbearing age.
  • Pregnancy is a significant consideration for SLE patients and their physicians.
  • While pregnancy outcomes have improved, risks remain for pregnant women with SLE.

Purpose of the Study:

  • To highlight the importance of pregnancy in women with SLE.
  • To emphasize the ongoing efforts to further improve pregnancy outcomes in SLE.
  • To recommend optimal management strategies for pregnant SLE patients.

Main Methods:

  • Review of current research and clinical considerations for SLE during pregnancy.
  • Emphasis on multidisciplinary care approaches.

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Isolation of Leukocytes from the Murine Tissues at the Maternal-Fetal Interface
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Last Updated: Mar 16, 2026

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Main Results:

  • Pregnancy outcomes in SLE patients have significantly improved over recent decades.
  • Pregnant women with SLE continue to face varying levels of risk.

Conclusions:

  • Joint care involving specialized multidisciplinary teams, including rheumatologists and obstetricians, is recommended.
  • This collaborative approach aims to achieve the best possible outcomes for both mother and child.