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Evolution of hypothalamic lipoma after Roux-en-Y gastric bypass.
M Bretault1, S Czernichow2,3, L Ouvry1
1Department of Nutrition, Ambroise Paré Hospital, AP-HP, Versailles Saint-Quentin en Yvelines University, Boulogne-Billancourt, France.
European Journal of Clinical Nutrition
|August 11, 2016
Summary
Severe obesity linked to hypothalamic lipomas can be effectively managed with Roux-en-Y gastric bypass. This bariatric surgery led to significant weight loss in an adult patient, with the hypothalamic lipoma remaining stable.
Area of Science:
- Neuroendocrinology
- Bariatric Surgery
- Radiology
Background:
- Severe obesity is frequently associated with hypothalamic disorders.
- Hypothalamic lipomas are rare causes of obesity, with limited pediatric case reports.
- This study focuses on an adult case of hypothalamic lipoma and severe obesity.
Observation:
- A case of an adult male presented with severe obesity.
- The patient had a hypothalamic lipoma attached to the floor of the third ventricle.
- He underwent Roux-en-Y gastric bypass surgery.
Findings:
- The patient experienced substantial weight loss: 38 kg at 6 months and 59 kg at 12 months post-surgery.
- Brain magnetic resonance imaging (MRI) confirmed the stability of the hypothalamic lipoma size at 6 and 12 months.
- Weight loss was consistent with expectations for severe obesity treated with bariatric surgery.
Implications:
- Roux-en-Y gastric bypass is a viable treatment option for severe obesity in adults with hypothalamic lipomas.
- Bariatric surgery can lead to significant weight reduction without adversely affecting the hypothalamic lipoma.
- Further research into the neuroendocrine and surgical management of hypothalamic obesity is warranted.
