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Expanding the donor pool: regional variation in pediatric organ donation rates
Justin Godown1, Meghann McKane2, Kari Wujcik1
1Division of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
Insights
Pediatric organ donation rates have declined recently, particularly among adolescents. Optimizing donation in lower-performing regions could increase pediatric donors by 24% annually.
Area of Science:
- Pediatric Organ Donation
- Transplant Medicine
- Public Health
Background:
- Limited data exist on pediatric organ donation rates.
- Understanding trends and regional variations is crucial for improving donation.
- Recent declines in pediatric deceased organ donors, especially adolescents, warrant investigation.
Purpose of the Study:
- To analyze trends in pediatric organ donation over time.
- To evaluate regional disparities in pediatric deceased organ donation rates.
- To identify opportunities for expanding the pediatric donor pool.
Main Methods:
- Utilized data from the Organ Procurement and Transplantation Network (OPTN).
- Indexed deceased pediatric organ donors using regional mortality data from the National Center for Health Statistics.
- Compared donation rates across UNOS regions and two distinct time periods.
Main Results:
- A decline in deceased pediatric organ donors was observed in the recent era, primarily due to fewer adolescent donors.
- Significant regional variations in pediatric organ donation rates exist across all age groups.
- Identified high- and low-performing regions for pediatric deceased organ donation.
Conclusions:
- Optimizing organ donation in underperforming regions presents an opportunity to expand the donor pool.
- If all regions matched the highest donation rates, an estimated 24% increase in pediatric donors (215 annually) could be achieved.
- Addressing regional disparities is key to increasing pediatric organ availability for transplantation.
Abstract:
There are limited published data on pediatric organ donation rates. The aim of this study was to describe the trends in pediatric organ donation over time and to assess the regional variation in pediatric deceased organ donation. OPTN data were utilized to assess the trends in pediatric organ donation over time. The number of deceased pediatric organ donors was indexed using regional mortality data obtained from the National Center for Health Statistics and compared across UNOS regions and two different eras. The number of pediatric deceased organ donors has declined in the recent era, largely driven by fewer adolescent donors. For all age groups, there is significant regional variation in organ donation rates, with identifiable high- and low-performing regions. Expansion of the donor pool may be possible by optimizing organ donation in regions demonstrating lower recruitment of pediatric donors. Using the region with the highest donation rate for each age group as the gold standard, we estimate a potential 24% increase in the number of donors if all regions performed comparably, equating to 215 new pediatric donors annually.
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