Related Experiment Video

Updated: Mar 16, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

4.2K

Novel melanoma therapy

Eddy C Hsueh1, Kalyan C Gorantla1

  • 1Division of General Surgery, Department of Surgery, Saint Louis University, 3635 Vista at Grand Blvd, St. Louis, MO 63110 USA.

Experimental Hematology & Oncology
|August 11, 2016
PubMed

Insights

New melanoma treatments are rapidly evolving, making treatment decisions more complex. This review guides rational choices for metastatic melanoma patients using novel therapies.

Area of Science:

  • Oncology
  • Dermatology
  • Pharmacology

Background:

  • Metastatic melanoma treatment is rapidly advancing with new effective agents.
  • Combination therapies show promise but increase treatment algorithm complexity.

Purpose of the Study:

  • To review recent advancements in novel melanoma therapies.
  • To provide guidance for rational decision-making in metastatic melanoma treatment.

Main Methods:

  • Literature review of recent reports on novel melanoma therapy.
  • Analysis of treatment outcomes for monotherapy versus combination therapy.

Main Results:

  • Emerging effective agents are changing the treatment paradigm.
  • Combination therapies offer improved outcomes but require careful patient stratification.

Conclusions:

  • Rational decision-making is crucial for optimizing metastatic melanoma treatment.
  • Understanding novel therapies aids in managing treatment complexity.
Keywords:
Checkpoint inhibitorsMetastatic melanomaTargeted therapy

More Related Videos

A 3D Organotypic Melanoma Spheroid Skin Model08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

16.7K
Author Spotlight: Recreating Melanoma Complexity with Patient-Derived Organoids for Immunotherapy Evaluation05:33

Author Spotlight: Recreating Melanoma Complexity with Patient-Derived Organoids for Immunotherapy Evaluation

Published on: September 6, 2024

2.4K

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.1K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

1.7K
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
6.5K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.9K
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

1.5K