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Updated: Mar 16, 2026
In situ Quantification of Pancreatic Beta-cell Mass in Mice
Published on: June 7, 2010
Data on morphometric analysis of the pancreatic islets from C57BL/6 and BALB/c mice
Thiago Aparecido da Silva1, Robertha Mariana Lemes2, Carlo Jose Freire Oliveira3
1Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos da Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Abstract:
The endocrine portion of the pancreas, which is characterized by pancreatic islets, has been widely investigated among different species. The BALB/c and C57BL/6 mice are extensively used in experimental research, and the morphometric differences in the pancreatic islets of these animals have not been evaluated so far. Thus, our data have a comparative perspective related to the morphometric analysis of area, diameters, circularity, and density of pancreatic islets from BALB/c and C57BL/6 mice. The data presented here are focused to evaluate the differences in morphology of pancreatic islets of two common laboratory mouse strains.
