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Related Experiment Video

Updated: Mar 16, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
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VITRECTOMY FOR MACULAR RETINOSCHISIS WITHOUT A DETECTABLE OPTIC DISK PIT.

Masatoshi Haruta1, Ryoji Yamakawa

  • 1Department of Ophthalmology, Kurume University School of Medicine, Fukuoka, Japan.

Retina (Philadelphia, Pa.)
|August 11, 2016
PubMed
Summary

Vitrectomy effectively treated macular retinoschisis without optic disk pits, improving retinal anatomy and visual acuity. This suggests a distinct pathogenesis for this condition compared to optic pit maculopathy.

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Area of Science:

  • Ophthalmology
  • Retinal Diseases

Background:

  • Macular retinoschisis can occur without a detectable optic disk pit.
  • The pathogenesis of macular retinoschisis without optic disk pit is not fully understood.
  • Optic pit maculopathy is a related condition but differs in the presence of an optic pit.

Purpose of the Study:

  • To assess the effectiveness of vitrectomy for treating macular retinoschisis.
  • To evaluate outcomes in patients lacking optic disk pits.

Main Methods:

  • Retrospective interventional case series of eight patients.
  • Exclusion criteria included optic disk pit, vitreomacular traction, or high myopia.
  • Six patients underwent vitrectomy with internal limiting membrane peeling and fluid-air exchange.

Main Results:

  • Macular retinoschisis resolved or reduced in all six treated eyes.
  • Significant improvement in mean central foveal thickness post-vitrectomy.
  • Mean best-corrected visual acuity improved from 20/52 pre-surgery to 20/31 post-surgery.

Conclusions:

  • Vitrectomy appears effective for macular retinoschisis lacking optic disk pits.
  • Intraoperative findings suggest a unique pathogenesis for this condition.
  • Further research may clarify the distinct mechanisms involved.