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Burden of Rotavirus Diarrhea in Under five Indian Children

Ashok Kumar1, Sriparna Basu, Vipin Vashishtha

  • 1Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India and Indian Academy of Pediatrics, Kailash Darshan, Kennedy Bridge, Mumbai, India. Correspondence to: Professor Ashok Kumar, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India. ashokkumar_bhu@hotmail.com.

Indian Pediatrics
|August 11, 2016
PubMed

Insights

Rotavirus diarrhea is a significant health issue in Indian children, with varied prevalence in hospitalized and community settings. Common rotavirus strains include G1, G2, and untypeable strains, showing regional differences.

Area of Science:

  • Pediatric Infectious Diseases
  • Gastroenterology
  • Public Health Epidemiology

Background:

  • Rotavirus is a leading cause of severe diarrhea in young children globally.
  • The epidemiological burden of rotavirus diarrhea in Indian children requires comprehensive understanding.
  • This study addresses the need for established data on rotavirus disease impact in India.

Purpose of the Study:

  • To review the epidemiology of rotavirus diarrhea in Indian children.
  • To analyze molecular serotypes and mortality associated with rotavirus diarrhea.
  • To assess rotavirus prevalence in both hospitalized and community settings in India.

Main Methods:

  • Systematic literature search of multiple databases (Medline, PubMed, IndMed) and official websites.
  • Inclusion of human studies in English, focusing on children aged 0-5 years.
  • No restrictions on study design or publication time frame.

Main Results:

  • Rotavirus diarrhea prevalence varied significantly across Indian regions, from 4.6% to 89.8% in hospitalized children and 4% to 33.7% in the community.
  • G1, G2, and untypeable rotavirus strains were predominant, with notable regional variations in strain prevalence.
  • Rotavirus was a significant cause of nosocomial diarrhea, identified in 5.2% to 80.5% of cases.

Conclusions:

  • Rotavirus diarrhea presents a substantial burden in Indian children, with considerable regional disparities in prevalence.
  • Specific rotavirus G serotypes (G1, G2, untypeable) are common, but regional variations exist.
  • Further research is needed to establish the precise mortality data for rotavirus diarrhea in India.
Abstract

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