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Interpretation of Rotavirus positivity Patterns Across India
S Venkatasubramanian1, C P Girish Kumar, Sanjay Mehendale
1National Institute of Epidemiology, Indian Council of Medical Research, Chennai, India. Correspondence to: Dr S Venkatasubramanian, National Institute of Epidemiology, Indian Council of Medical Research, II Main Road, TNHB, Ayapakkam, Chennai 600 077, India. subramanianv89@yahoo.co.in.
Indian Pediatrics
|August 11, 2016
Summary
This study introduces new statistical methods to track rotavirus spread. These measures help analyze disease burden variations in children across different seasons, ages, and regions.
Area of Science:
- Epidemiology
- Biostatistics
- Public Health
Background:
- Rotavirus is a leading cause of acute gastroenteritis in children worldwide.
- Effective surveillance requires accurate statistical measures to understand disease patterns and variations.
Purpose of the Study:
- To analyze variations in rotavirus positivity using simple alternative statistical measures.
- To assess the utility of these measures in disease surveillance programs.
Main Methods:
- Hospital-based rotavirus surveillance data from children with acute gastroenteritis (2005-2009).
- Calculation of prevalence, adjusted proportions, and symmetrized index to analyze rotavirus variation.
Main Results:
- Overall rotavirus prevalence was 40%.
- Adjusted proportion analysis indicated significant deviations in specific seasons, age groups (<12 and 12-23 months), and regions (East and South).
- The symmetrized index showed higher variation estimates annually, except in 2006.
Conclusions:
- The proposed statistical measures offer refined insights into disease spread extent.
- These methods aid in evaluating the load and pattern of rotavirus disease burden over time and across different geographical areas.
