Related Experiment Video
Updated: Mar 16, 2026
Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
Published on: January 28, 2019
Interpretation of Rotavirus positivity Patterns Across India
S Venkatasubramanian1, C P Girish Kumar, Sanjay Mehendale
1National Institute of Epidemiology, Indian Council of Medical Research, Chennai, India. Correspondence to: Dr S Venkatasubramanian, National Institute of Epidemiology, Indian Council of Medical Research, II Main Road, TNHB, Ayapakkam, Chennai 600 077, India. subramanianv89@yahoo.co.in.
Objective:
To analyze variation in rotavirus-positivity using simple alternative statistical measures.
Methods:
Hospital-based rotavirus surveillance among children admitted with acute gastroenteritis between 2005 and 2009. Prevalence, adjusted proportions and symmetrized index were calculated.
Results:
Rotavirus prevalence was 40% (range 37% - 44%). Adjusted proportion analysis revealed higher level of deviation from annual prevalence in seasons (December to February and September to November); age groups (<12 months and 12-23 months) and regions (East and South). Analysis of symmetrized index revealed higher estimates of variation in all years, except in 2006.
Conclusions:
Proposed statistical measures are useful as refined measures to study extent of disease spread in surveillance programmes, aiding evaluation of the load and pattern of disease burden in different regions over time.
