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Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
Published on: September 19, 2018
Population-based study of ruptured abdominal aortic aneurysm.
M T Laine1, S J Laukontaus2, I Kantonen2
1Department of Vascular Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. matti.laine@hus.fi.
Ruptured abdominal aortic aneurysm (rAAA) incidence and mortality are decreasing in southern Finland. However, high mortality persists due to patients dying before hospital arrival.
Area of Science:
- Vascular surgery
- Epidemiology
- Public health
Background:
- Abdominal aortic aneurysm (AAA) rupture incidence has shown a declining trend.
- This study investigates trends in ruptured AAA (rAAA) incidence within the Helsinki and Uusimaa (HUS) hospital district in Finland.
- A population-based retrospective review was conducted for the period 2003-2013.
Purpose of the Study:
- To evaluate temporal trends in the incidence of ruptured abdominal aortic aneurysms (rAAA).
- To assess the mortality rates associated with rAAA in a defined Finnish population.
- To analyze patient outcomes and treatment turn-down rates for rAAA.
Main Methods:
- Retrospective review of a population-based cohort of rAAA patients in the HUS district (1.5 million inhabitants).
- Data collected from the Helsinki University Hospital vascular registry and Statistics Finland's cause of death registry.
- Analysis included patient demographics, hospital arrival status, surgical treatment rates, and 30-day mortality.
Main Results:
- A total of 712 patients with rAAA were identified; 46.3% arrived alive at the hospital.
- The 30-day survival rate for all rAAA patients was 27.9%.
- The incidence of rAAA was 4.3 per 100,000 inhabitants, with a decreasing trend observed over the 11-year study period.
Conclusions:
- The incidence of ruptured abdominal aortic aneurysms (rAAA) is declining in the HUS district.
- Despite decreasing incidence, mortality from rAAA remains high, with a significant proportion of deaths occurring pre-hospital.
- Improved pre-hospital care and faster access to vascular surgery may be crucial for reducing rAAA mortality.
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