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Efficacy of fluralaner in 17 dogs with sarcoptic mange
Camilo Romero1, Rafael Heredia2, Jocelyn Pineda3
1Centro Universitario UAEM Amecameca, Universidad Autónoma del Estado de México, Carretera Amecameca-Ayapango Km 2.5, Amecameca de Juárez, CP 56900, Estado de México, México. cromeron@uaemex.mx.
Background:
There are few licensed options for the treatment of canine sarcoptic mange.
Objective:
To evaluate the efficacy of fluralaner in dogs with sarcoptic mange infestation.
Animals:
Seventeen dogs with a diagnosis of Sarcoptes scabiei based on positive skin scrapings.
Methods:
A single dose of oral fluralaner was administered according to the manufacturer's instructions. Assessments of pruritus and lesions were performed every 7 days for 1 month.
Results:
By Day 14 post-treatment, skin scrapings from all dogs were negative for mites. At the beginning of the study there was a negative correlation between body weight of the subject and pruritus [Pearson correlation coefficient (PCC) = -0.396, P = 0.007] and a positive correlation between pruritus and lesion severity (PCC 0.755, P = 0.0001). Significant decreases in lesion size and pruritus were observed within the first 14-21 days, respectively, and improvement in these parameters continued until the end of the study at Day 28.
Conclusion:
Fluralaner was effective in eliminating scabies mites within 14 days and significantly resolved the clinical signs associated with sarcoptic mange within 21 days after a single dose.
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