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Thyroid abnormalities in paediatric patients with vitiligo: retrospective study

Demet Kartal1, Murat Borlu1, Salih Levent Çınar1

  • 1Department of Dermatology and Venereology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.

Postepy Dermatologii I Alergologii
|August 12, 2016
PubMed

Insights

Screening for thyroid disorders is recommended in children diagnosed with nonsegmental vitiligo, as a significant association was found. This study highlights the importance of early detection in pediatric patients with vitiligo.

Area of Science:

  • Pediatric Dermatology
  • Endocrinology
  • Autoimmune Diseases

Background:

  • The link between vitiligo and thyroid disease requires further investigation, particularly in pediatric populations.
  • Vitiligo, a condition causing skin depigmentation, can be associated with underlying autoimmune disorders.

Purpose of the Study:

  • To determine the incidence of vitiligo and associated thyroid disorders in children.
  • This study provides the first data from Middle Anatolia and the second from Turkey on this pediatric cohort.

Main Methods:

  • A retrospective chart review was conducted.
  • Paediatric patients admitted to the dermatology department with vitiligo were assessed for thyroid abnormalities.

Main Results:

  • 155 pediatric patients (mean age 8.6 years) were included; 90% had nonsegmental vitiligo.
  • Thyroid abnormalities were detected in 22% of patients, all of whom had nonsegmental vitiligo.
  • A statistically significant association (p < 0.05) was observed between vitiligo type and thyroid disease parameters.

Conclusions:

  • Screening for thyroid dysfunction in children with nonsegmental vitiligo is advisable.
  • Early detection and management of thyroid disorders can improve outcomes for pediatric patients with vitiligo.
Abstract

Keywords:
thyroid abnormalitiesvitiligo

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