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Palate size and shape in schizophrenia
Mehtap Delice1, Ozlem Gurbuz2, Ceyhan Oflezer3
1Department of Psychiatry, Bakirkoy Training and Research Hospital for Psychiatry, Neurology and Neurosurgery, Istanbul, Turkey.
Psychiatry Research
|August 12, 2016
Summary
Patients with schizophrenia have wider and deeper palates compared to controls. These palate shape differences may serve as potential markers for early detection of schizophrenia.
Area of Science:
- Neuroscience
- Genetics
- Anthropology
Background:
- Minor physical anomalies are associated with schizophrenia.
- The palate's development is linked to facial and brain structures.
Purpose of the Study:
- To compare palate dimensions and form between schizophrenia patients and controls.
- To identify potential physical markers for schizophrenia.
Main Methods:
- Dental stone casts of 127 schizophrenia patients and 127 controls were analyzed.
- Palate dimensions (length, width, depth) were measured using digital calipers and a palatometer.
- Multivariate analysis was used to identify significant risk factors.
Main Results:
- Palate length did not significantly differ between groups.
- Palate width and depth were significantly greater in the schizophrenia group.
- Furrowed palate shape, increased palate width, and ellipsoid maxillary arch shape were significant risk factors.
Conclusions:
- Schizophrenia patients exhibit distinct palate morphology.
- These findings suggest palate abnormalities may indicate embryological dysmorphogenesis related to schizophrenia.
- Palate parameters may serve as potential biomarkers for schizophrenia.
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