Bowenoid Actinic Keratosis and Bowen's Disease Treated Successfully with Ingenol Mebutate

Mosab T Mohanna1, Günther F L Hofbauer

  • 1Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Dermatology (Basel, Switzerland)
|August 12, 2016
PubMed

Ingenol mebutate (IM) is a topical pharmacotherapy approved in Switzerland since 2012 for treating non-hypertrophic, non-hyperkeratotic actinic keratosis (AK). We report 2 cases with off-label use of IM. The first case of bowenoid AK was treated with 150 μg IM for 3 consecutive days with an almost complete clinical remission of the lesion. The second case of Bowen's disease was treated with 500 μg IM for 2 consecutive days leading to complete clinical remission.

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